Associate Professor
University of Texas Southwestern Medical Center
Dallas, TX, United States
Dan Huang, M.D. and Ph.D., is an Associate Professor in the Cecil H. and Ida Green Center for Reproductive Biology Sciences and the Department of Obstetrics and Gynecology at UT Southwestern Medical Center. In 2009, Dr. Huang completed her M.D. and Ph.D. in Medicine at Tongji Medical College, Huazhong University of Science and Technology (HUST), China. She then worked as a cardiologist and clinician scientist in Wuhan Union Hospital, HUST. She was promoted to Associate Professor in 2012. She joined the faculty of UT Southwestern Medical Center in December 2024. Dr. Huang is interested in exploring the mechanisms of chromatin-dependent regulation of gene expression that lead to the development of cardiovascular diseases, metabolic disorders, and cancers. Utilizing an integrated approach that spans from molecular, cellular, proteomic, and genomic analyses, to mouse genetic models, she has focused on the key aspects of post-translational modifications in the regulation of chromatin and transcription, including (1) epigenomic regulation by ADP-ribosylation and poly(ADP-ribose)polymerase (PARP) enzymes that catalyze the modification; (2) regulation of transcription factors by nuclear PARPs and ADP-ribosylation; and (3) inter-relationship network between histone post-translational modifications. Throughout her career as a clinician scientist, she has placed a great emphasis on connecting molecular mechanisms to biological outcomes, and identifying new biomarkers and therapeutic targets for cardiovascular diseases, metabolic disorders, and cancers.
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ORF21 - Metabolic GPCR Networks in Adipose, Muscle and Islets: Mechanisms to Medicines (45 min.)
Sunday, June 14, 2026
9:30 AM - 10:15 AM CT
Monday, June 15, 2026
10:30 AM - 11:00 AM CT