ORF21 - Metabolic GPCR Networks in Adipose, Muscle and Islets: Mechanisms to Medicines

ORF Chair-Primary(s)

• 

  Dan Huang, MD, PhD (she/her/hers)

  Associate Professor
  University of Texas Southwestern Medical Center
  Dallas, TX, United States

  Disclosure(s): No financial relationships to disclose

Presentations:

• 9:30 AM - 9:35 AM CT

  A Golgi-ER Ubiquitin Network Governing PD-L1 Stability in Islet Beta Cells
  

  Rapid and Poster Presenter: Kerim B. Kaylan, MD, PhD (he/him/his) – UNIVERSITY OF CHICAGO

  Submitting author: Fei Huang, MD (he/him/his) – University of Chicago

  Co-Author: Fei Huang, MD (he/him/his) – University of Chicago

  Co-Author: Charanya Muralidharan, PhD (she/her/hers) – UNIVERSITY OF CHICAGO

  Co-Author: Soumyadeep Sarkar, Ph.D. – PNNL

  Co-Author: Ernesto S. Nakayasu, PhD (he/him/his) – Pacific Northwest National Laboratory

  Co-Author: Bobbie-Jo Webb-Robertson, n/a (she/her/hers) – Pacific Northwest National Laboratory

  Senior Author/Primary Investigator: Sarah A. Tersey, PhD – University of Chicago

  Senior Author/Primary Investigator: Raghavendra Mirmira, MD, PhD – The University of Chicago
• 9:35 AM - 9:40 AM CT

  Syndecans Act as GPCR Accessory Proteins Modulating MC4R Signaling
  

  Submitting author: Noa J.M. Mutsters, MSc – Erasmus MC

  Rapid and Poster Presenter: Noa J.M. Mutsters, MSc – Erasmus MC

  Senior Author/Primary Investigator: Jenny A. Visser, PhD (she/her/hers) – Erasmus MC

  Co-Author: Afonso de Oliveira Santos Goulart, MSc – Erasmus MC

  Co-Author: Patric J.D. Delhanty, PhD – Erasmus MC Rotterdam
• 9:40 AM - 9:45 AM CT

  Angiotensin 1-7 (Ang1-7) as a Potential Therapeutic Modulator of Skeletal Muscle Inflammation and Atrophy
  

  Submitting author: Yonit Marcus-Perlman (she/her/hers) – Tel Aviv Medical Center

  Rapid and Poster Presenter: Yonit Marcus-Perlman (she/her/hers) – Tel Aviv Medical Center

  Co-Author: Gabi Shefer, PhD (she/her/hers) – Tel Aviv Medical Center

  Co-Author: Gilad Lehman, PhD – Tel Aviv Medical center

  Co-Author: Yona Greenman, MD PhD (she/her/hers) – Tel Aviv Sourasky Medical Center

  Senior Author/Primary Investigator: Naftali Stern, MD – Sourasky Medical Center, Tel Aviv, Israel
• 9:45 AM - 10:00 AM CT

  Calcium-Driven Gs-to-Gq Switching of GLP-1 Receptor Signaling in Pancreatic Β-Cells under High-Glucose Conditions
  

  Submitting author: Hirofumi Horikoshi, MD and PhD – Department of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine

  Oral Abstract Presenter: Hirofumi Horikoshi, MD and PhD – Department of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine

  Co-Author: Junichiro Sato, MD and PhD – Department of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine

  Co-Author: Maho Taguchi, MD – Department of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine

  Co-Author: Katsunori Manaka, MD and PhD – Department of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine

  Co-Author: Masaomi Nangaku, MD and PhD – Department of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine

  Senior Author/Primary Investigator: Taroh Iiri, MD and PhD – Department of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine

  Senior Author/Primary Investigator: Noriko Makita, MD and PhD – Department of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine
• 10:00 AM - 10:15 AM CT

  Regulation of Adaptive Thermogenesis by TrkB in Brown Adipose Tissue
  

  Co-Author: Elsie Cht Yu Iu, PhD – The University Of Hong Kong

  Co-Author: Mengxin Chen, BSc – Nanchang University

  Co-Author: Limin Zhao, PhD – Nanchang University

  Co-Author: Xiuying Yang, PhD – Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College

  Submitting author: Chi Bun Chan, PhD (he/him/his) – The University of Hong Kong

  Oral Abstract Presenter: Chi Bun Chan, PhD (he/him/his) – The University of Hong Kong

  Senior Author/Primary Investigator: Chi Bun Chan, PhD (he/him/his) – The University of Hong Kong