Professor
Oregon Health & Science University
Portland, OR, United States
Thomas S. Scanlan, PhD, is a Professor of Physiology & Pharmacology in the Department of Chemical Physiology & Biochemistry at Oregon Health & Science University. Dr. Scanlan's research focuses on thyroid hormone action in general, and in particular on the discovery and development of tissue selective thyroid hormone agonist molecules as research tools and novel therapeutic agents. Dr. Scanlan's lab invented the T3 agonist sobetirome which has been widely studied as a tool compound and went through phase 1 clinical development as a cholesterol-lowering agent. Recently, Dr. Scanlan's lab created a T3 agonist prodrug strategy for selective delivery of T3 agonists to the brain from a systemically administered dose. These novel agents have been used to study thyroid hormone action in the brain and spinal cord and one drug from this class is currently in Phase 2 clinical development for the treatment of major depressive disorder (MDD) and bipolar depression (BD).
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SY45-03 - Thyroid Hormone Analogues for CNS Diseases
Monday, June 15, 2026
11:14 AM - 11:36 AM CT