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Bone and Mineral Metabolism

SUN-831 - Predictors of hungry bone syndrome after parathyroid adenoma surgery in Basrah

Sunday, June 14, 2026
9:00 AM - 4:00 PM CT

    Senior Author/Primary Investigator(s)

  • HA

    Haider Ayad Alidrisi, MD FIBMS CABM (Med) CABM (Endo) FACE

    Assistant professor
    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

    • Co-Author(s)

  • OA

    Osama Abbas, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • KR

    Khulood Reman, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • AA

    Ahmed Abdul-Zahraa, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • AA

    Amenah Abulkareem, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • HA

    Hussein Albnder, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • HJ

    Hussein Jbarah, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • JA

    Jafer Alsamer, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • AA

    Ali Al-Abadi, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • HA

    Hussein Al-Sarayefi, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • FA

    Fawatim Al-Musawi, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

  • NA

    Noor Abdulimam, MD

    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Iraq

    • Late-Breaking Poster Presenter(s)

  • AM

    Abbas Ali Mansour, MD

    Professor
    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Al Basrah, Iraq

    • Co-Author(s)

  • AM

    Abbas Ali Mansour, MD

    Professor
    University of Basrah, Faiha Specialized Diabetes Endocrine and Metabolism Center
    Basrah, Al Basrah, Iraq



Background:
The definitive treatment of primary hyperparathyroidism (PHPT)is surgical removal of the parathyroid-secreting adenoma. While it is almost always successful, it is commonly associated with rapid fall in serum calcium (Ca) i.e.: hungry bone syndrome (HBS). We aimed in this study to assess the prevalence of HBS and its predictors.

Method:
It was a retrospective study including 77 patients who were treated by parathyroidectomy for PHPT in a single center in Basrah, Southern Iraq, between 2012 to 2025. HBS was diagnosed based on combination of clinical and biochemical criteria.

Results:
HBS was prevalent in 23 (29%) patients. We found that HBS was associated with patients’ characteristics in the form of younger age, higher parathormone, higher glomerular filtration rate, higher alkaline phosphatase (ALP), presence of fracture, and absence of Type 2 diabetes mellitus. A stepwise binary regression analysis confirmed that higher baseline ALP was strongest independent predictors for HBS.

Conclusion:
HBS prevalence was high in our patients. Patients with high baseline ALP were high likely to develop HBS and need to be closely followed in the early post parathyroidectomy period.
Keywords: primary hyperparathyroidism, hungry bone disease, alkaline phosphatase.

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