The Jewish Hospital of Cincinnati - Mercy Health Cincinnati, Ohio, United States
We present a patient with recurrent thunderclap headaches and hypertension who incidentally was found to have a pheochromocytoma. Upon admission to the hospital for acute encephalopathy, initial workup including serum studies, computed tomography of the brain, magnetic resonance imaging (MRI) of the brain, and cerebrospinal studies were unremarkable. Repeat brain MRI several weeks following demonstrated bilateral, frontal subacute ischemia, leading to the diagnosis of reversible cerebral vasoconstriction syndrome (RCVS). Existing literature has identified pheochromocytoma as a possible precipitant of RCVS, however the evidence for this relies upon theoretical understandings of the pathophysiology of RCVS and few case reports identifying co-occurring pheochromocytomas and RCVS.
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