Topic: Cardiovascular Endocrinology
Mattia Quattrocelli
Disclosure information not submitted.
Mitchell Lazar, MD,PhD
Director, Institute for Diabetes, Obesity and Metabolism
University of Pennsylvania
Philadelphia, PA, United States
Disclosure(s): Eccogene Inc.: Advisory Board (); Flagship Pioneering Medicines: Advisory Board (); Flare Therapeutics, Inc: Advisory Board (), Owner/Co-Owner Founder/Co-Founder (); Pfizer Inc: Board Member/Officer/Trustee ()
Circadian rhythms and sleep play a central role in regulating metabolism, immune function, and inflammation, all of which are key drivers of cardiovascular disease. This session will explore how biological clocks interact with immune and metabolic systems to influence cardiometabolic health, and how disruption of these rhythms contributes to cardiovascular risk. Mechanistic insights into endocrine-circadian interactions will be discussed alongside emerging evidence on circadian regulation of inflammation. The session will also highlight the clinical relevance of sleep duration and quality, and how improving sleep and circadian alignment may reduce cardiometabolic risk. By linking fundamental circadian biology with clinical practice, this session aims to provide a translational perspective on how "clock-based" mechanisms can inform new approaches to cardiovascular disease prevention and management.
Symposium Speaker: Clara Peek, PhD – Northwestern University
Symposium Speaker: David Ray, MB ChB PhD (he/him/his) – university of Oxford
Symposium Speaker: Esra Tasali, MD – University of Chicago
Symposium Speaker: Morag J. Young, PhD (she/her/hers) – Baker Heart and Diabetes Institute