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Topic: Tumor Biology
Session Type: Symposium

SY54 - Environmental Exposures and Development of Hormone-Dependent Cancers

Monday, June 15, 2026
4:30 PM - 6:00 PM CT
Location: Room 181AB

    Symposium Chair(s)

  • LT

    Lindsey Treviņo, PhD

    Associate Professor
    City of Hope National Medical Center
    Duarte, CA, United States

    Disclosure(s): No financial relationships to disclose

    • Symposium Speaker(s)

  • Zeynep Madak Erdogan, PhD

    Professor
    UIUC
    Urbana, IL, United States

    Disclosure(s): No financial relationships to disclose

  • AS

    Ana Soto, MD (she/her/hers)

    Professor
    Tufts University School of Medicine
    BOSTON, MA, United States

    Disclosure information not submitted.

  • Gail Prins, PhD

    Michael Reese Distinguished Professor
    University of IL - Chicago
    Chicago, IL, United States

    Disclosure(s): No financial relationships to disclose

  • Charlotte Kuperwasser, PhD

    Professor & Director
    Tufts University School of Medicine
    Boston, MA, United States

    Disclosure(s): No relevant disclosure to display

Disclosure(s):
Lindsey Treviņo, PhD: No financial relationships to disclose
Zeynep Madak Erdogan, PhD: No financial relationships to disclose
Gail S. Prins, PhD: No financial relationships to disclose
Charlotte Kuperwasser, PhD: No relevant disclosure to display

Incidence of hormone dependent cancers are set to increase over the coming decades and there is growing evidence that exogenous factors impact the endocrine drivers of such diseases. We don't fully understand the influence of
endocrine disrupting chemicals on cancer incidence and with the introduction of thresholds for steroid hormones in drinking water (EU directive) it is timely to focus on environmental factors that may impact the development of endocrine related cancers.

Learning Objectives:

  • Discuss how the lived environment may influence breast cancer risk and aggressiveness through hormones and inflammation.
  • Understand how prostate cancer risk in the offspring is altered by exposures during gestation.
  • Discuss how nongenetic/epigenetic changes that drive cancer risk are influenced by endocrine-disrupting chemicals.

Presentations:

  • 4:30 PM - 6:00 PM CT
    EDCs in Fetal Exposure and Cancer Risk

    Symposium Speaker: Ana M. Soto, MD (she/her/hers) – Tufts University School of Medicine

  • 4:30 PM - 6:00 PM CT
    Impact of Socio-Environmental Stressors on Breast and Lung Cancers

    Symposium Speaker: Zeynep Madak Erdogan, PhD – UIUC

  • 4:30 PM - 6:00 PM CT
    Modeling Endocrine Disruption in Human Breast Development Using a 3D Organoid Platform

    Symposium Speaker: Charlotte Kuperwasser, PhD – Tufts University School of Medicine

  • 4:30 PM - 6:00 PM CT
    PFAS Exposures Shift Human Prostate Cancer Stem Cell Metabolism, Alter Signaling Pathways and Increase Aggressive Behavior

    Symposium Speaker: Gail S. Prins, PhD – University of IL - Chicago