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Sean Hartig, PhD

Professor
Baylor College of Medicine
Houston, TX, United States

Dr. Sean Hartig earned his Ph.D. in Chemical Engineering from Vanderbilt University, followed by postdoctoral training in Cancer Biology at UT MD Anderson Cancer Center and in Molecular and Cellular Biology at Baylor College of Medicine. He joined the faculty on the research track in 2011 and was awarded tenure in 2022. Dr. Hartig currently serves as Director of the Cellular and Molecular Metabolism Core at the Houston Nutrition and Obesity Research Center, which secured NIH funding in 2025.
Dr. Hartig’s research has significantly advanced the understanding of the regulation of metabolic phenotypes, with an emphasis on energy balance changes occurring in obesity and type 2 diabetes. His laboratory employs preclinical models, mass spectrometry-based metabolomics, and integrated genome-wide approaches to investigate mechanisms governing gene expression and metabolism in fat cells. His work has uncovered novel endocrine signals derived from white adipose tissue that confer protection against obesity-related complications. Dr. Hartig has received prestigious NIH F32 and K01 career development awards and has authored 85 peer-reviewed publications. His research program receives continuous funding from NIDDK since 2009 and is currently supported by three NIH R01 grants totaling over $1.1 million in direct costs. He contributes as a co-investigator on seven additional NIH R01-funded projects and as PI of the Cellular and Molecular Metabolism Core for the Houston Nutrition and Obesity Research Center (P30DK144025).

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