Background: Diabetic cheiroarthropathy (DCA) also called diabetic stiff hand syndrome, is a frequently overlooked musculoskeletal complication of diabetes mellitus characterized by painless, progressive limitation of hand joint mobility and positive prayer and tabletop signs. Its prevalence ranges from 8% to 58%( 1-3). It is strongly associated with diabetic kidney disease DCA may serve as a clinical marker of cumulative glycemic exposure and microvascular injury (4-6). This study aims to determine the frequency of DCA and its association with diabetic kidney disease. Methodology: This prospective cross-sectional study was conducted at the Asian Institute of Medical & Health Sciences after IRB approval. All consenting diabetic patients were consecutively enrolled; those with conditions affecting musculoskeletal assessment were excluded. Data on demographics, BMI, clinical history, musculoskeletal findings, and laboratory parameters were collected using a standardized questionnaire. Analysis was performed in SPSS version 26, with results presented as means ± SD and percentages.
Results: Among 100 patients, 33% had diabetic cheiroarthropathy. Skin thickening and limited joint mobility were present in 68% and 35% of patients, respectively, with 33% exhibiting both features. Diabetic nephropathy was significantly associated with limited joint mobility.
Conclusion: DCA was present in 1/3rd of patients, was significantly associated with diabetic nephropathy, conferring a more than twofold increased risk (OR 2.5, p = 0.042). Key words: Diabetes, Chieroarthropathy, Kidney function, Limited joint movements, Thick skin
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