Professor University of Maryland School of Medicine Baltimore, MD, United States
Disclosure(s):
Ryan C. Riddle, PhD: No financial relationships to disclose
Wnt signaling has emerged as a cornerstone in skeletal biology, driving innovations in bone health and regenerative therapies. This symposium brings together leading experts to explore how Wnt pathways orchestrate cellular metabolism, mechanotransduction, and therapeutic strategies for bone formation.
Learning Objectives:
Explain the role of Wnt signaling in bone biology and its integration with cellular metabolism and mechanotransduction.
Analyze how metabolic pathways and mechanical loading influence Wnt signaling to regulate bone formation and skeletal adaptation.
Evaluate current and emerging therapeutic strategies that harness Wnt signaling for anabolic bone regeneration, including antibody-based approaches.
Discuss translational implications of Wnt-targeted interventions for improving bone health and treating conditions such as osteoporosis and fracture healing.